I think that's Morgana from Dragon Age making out with an Asari from Mass Effect.

....Oh holy cow. In the bottle left corner with the poring...that's one of the Norns from Creatures, isn't it? Man, I haven't seen that game in years.

Is that Earthworm Jim? This is amazing!

Diablo, Cyberdemon (Doom series), Starcraft Ghost character(name?) and Kane (C&C series) all in the bottom right corner.

The art style really makes identifying some of these characters really tough although some are pretty obvious. Braid character, Fallout character and FF7 characters on the left side.

Oh,yeah and the girl that the big daddy is spanking may be the girl from F.E.A.R.

some update

some more updates

how do you edit the notes in the image? Theres a misassociation of Shub-Niggurath from Quake 1 as "Chasm: The rift"

>how do you edit the notes in the image?
>Theres a misassociation of Shub-Niggurath from Quake 1 as "Chasm: The rift"

Sorry for my bad english.

This is the final boss of the «Chasm: The Rift» (ancient and little-known 3D shooter from the creators of «Vivisector: Beast Within»). At this boss had to jump, then climb through the mouth inside, and finally cut his heart, then boss of agony, but the player dies with him.
Games featured the opportunity to shoot the monsters limbs, forcing them to change the tactics of warfare.
http://www.ag.ru/screenshots/chasm_the_rift

Ranger is just trying to climb inside and cut the heart. Also in this poster strive to combine similar items so there is no double meaning to specify Quake in one composition.

Oh gads, I think my brain just nerdgasmed.

Surprised that nobody noticed Heavy Weapons Guy over there.

блять, и тут кузьмичев

Blade runner interrogating a clone trooper? Now that's funny!

"блять, и тут кузьмичев" и не только тут ;)

Found Ghat from Xeno Clash (he's poking the Spore creature) but for some reason it won't let me add notes.

Just a very tiny piece of "Star Control 2: The Ur-Quan Masters" fan art here (Talana, a Syreen starbase commander. Blue skinned female near the upper left corner).

A new game "Free Stars: Children of Infinity" is being made as an official sequel to that old game. Should be fun.